Fleck corneal dystrophy is characterised by scattered small dots and larger oval grey-white opacities in all stromal layers. The intervening cornea is normally clear.

Congenital stromal corneal dystrophy is usually evident at birth or shortly after, presenting as bilateral diffuse corneal clouding with opacities in the anterior stroma.

Overview Meesmann epithelial corneal dystrophy References Overview Gene (OMIM No.) KRT12 (#601687) Function of gene/protein Protein: Cytokeratin 12 Expressed in...

Overview Meesmann epithelial corneal dystrophy References Overview Gene (OMIM No.) KRT3 (#148043) Function of gene/protein Protein: Cytokeratin 3 Expressed in...

Corneal dystrophies are a group of inherited eye conditions in which abnormal material builds up within the cornea. This can cause the cornea to lose its transparency and become cloudy. Some corneal dystrophies may not cause any symptoms, but others can cause discomfort, pain, dryness, light sensitivity and blurry vision.

Fuchs endothelial corneal dystrophy is the most common form of corneal dystrophy. Patients tend to notice gradual blurring of vision, usually worst in the mornings. It is due to progressive degeneration of corneal endothelial cells leading to corneal haziness.

Neuroprotective agents are a broad range of therapies that aim to slow or halt cell degeneration by promoting cell survival and preserving their function.