Overview Axenfeld-Reiger anomaly Primary congenital glaucoma Peters anomaly References Overview Gene (OMIM No.) FOXC1 (#601090) Function of gene/protein Protein: Forkhead...

Axenfeld-Reiger anomaly is a form of anterior segment dysgenesis with increased risk of glaucoma development. The main ocular feature is posterior embryotoxon. Other features include iris and pupil abnormalities. Axenfeld-Reiger syndrome is ARA with dental defect, craniofacial anomalies and redundant periumbilical skin.

Axenfeld-Reiger syndrome is a genetic condition that primarily affects the eyes. Patients are at high risk of developing glaucoma. ARS can also involve other parts of the body in some patients, primarily the face, teeth and umbilicus.