Information and support
How to see a genetic eye specialist?
Coping with sight loss
Eye Clinic Liaison Officers (ECLOs)
Education and learning
Family support service (FSS)
Registration for sight impairment
Charles Bonnet Syndrome (CBS)
Driving and alternative transport
Genetics basics and inheritance pattern
Genetic counselling and genetic testing: for patients
Genetic counselling: for professionals
Clinical genetic testing: for professionals
Microphthalmia, anophthalmia, coloboma (MAC) and aniridia
Cataract and lens associated
Anterior segment dysgenesis including glaucoma
Therapies under research
Searching for current research or trials
Research Opportunities At Moorfields
Dominant optic atrophy: for professionals
Dominant optic atrophy is the commonest form of inherited optic neruopathies, with majority of the cases associated with autosomal dominant OPA1 mutations. Patients tend to present with bilateral progressive painless visual loss without spontaneous recovery. About 20% of patients also have neurological symptoms, with sensorineural hearing loss being the most common.
Dominant Optic Atrophy: for patients
Dominant optic atrophy is an inherited condition that leads to progressive degeneration of the optic nerve. Patients tend to develop visual loss in both eyes around childhood or teenage years which gradually worsens.