Cornea

Overview

The cornea is a transparent structure situated at the front of the eye. It is also commonly known as the “clear window of the eye”. It has two main purposes, which are protecting the eye from injury and infection and focusing light into the eye. It has more light focusing power than the lens. It is made up of five different layers.


Layers of the cornea

  • Epithelium

This is the most superficial layer of the cornea. The cells here provide an optimal surface to keep the cornea moist and clear. These cells are constantly shed and replaced by stem cells located in the limbus. An imbalance in this process causes the eye to be chronically dry and irritable, leading to discomfort and visual deterioration.

This image demonstrates the location of the limbus. It appears as the junction between the coloured part of the eye and the white of the eye
Location of the corneal limbus
  • Bowman’s layer

This is a dense connective tissue layer separating the epithelium and stroma.

  • Stroma

This is the thickest layer of the cornea. It provides structural toughness to the cornea and the special arrangement of the cells here gives rise to its transparency.

  • Descemet’s membrane

This is a dense connective tissue layer separating the stroma and the endothelium.

  • Endothelium

This is the innermost layer. Cells here regulate the fluid content in the cornea. Damaged or diseased cells causes swelling of the cornea, disrupting its transparency and therefore affects vision.

This image shows the different layers of the cornea (clear window of the eye), with the epithelium being the most superficial, followed by the storm and the endothelium is the deepest layer.
The different layers of the cornea