Aniridia is a rare birth eye defect characterised by an under-developed or absent iris (no eye colour). It can be associated with WAGR syndrome, increasing the risk of developing Wilms tumour.

Aniridia is a a pan-ocular bilateral congenital eye anomaly characterised by complete or partial iris hypoplasia, foveal hypoplasia and early-onset nystagmus. Patients with WT1 deletion are at risk of developing Wilms tumour.

WAGR is a condition that affects multiple body systems. Its main features are Wilms tumour, aniridia, genitourinary abnormalities and range of developmental delays.

WAGR syndrome describes its four main features: Wilms tumour, aniridia, genitourinary anomalies and range of developmental delays. It is due to deletion of chromosome 11p13.